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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANLN
All Species:
14.24
Human Site:
S458
Identified Species:
28.48
UniProt:
Q9NQW6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQW6
NP_061155.2
1124
124199
S458
E
K
G
G
N
S
K
S
K
Q
L
E
T
K
Q
Chimpanzee
Pan troglodytes
XP_001169875
1125
124324
S459
E
K
G
G
N
S
K
S
K
Q
L
E
T
K
Q
Rhesus Macaque
Macaca mulatta
XP_001103129
1127
124400
S458
E
K
G
G
N
S
K
S
K
Q
L
E
T
K
Q
Dog
Lupus familis
XP_539518
1121
123493
K455
G
N
L
W
S
A
E
K
G
E
N
P
R
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K298
1121
122775
S453
E
K
N
E
K
S
R
S
K
H
L
E
T
K
Q
Rat
Rattus norvegicus
XP_225479
975
107264
S351
T
P
T
A
V
K
I
S
G
T
E
P
A
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418836
1121
123757
K455
A
E
R
S
E
S
S
K
R
K
L
P
E
A
K
Frog
Xenopus laevis
Q801E2
1116
122812
Q452
W
T
K
Q
E
D
E
Q
Q
G
T
F
P
E
T
Zebra Danio
Brachydanio rerio
NP_001096146
1153
127336
K481
T
T
A
A
L
T
E
K
Q
K
M
E
R
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4P1
1239
136015
R557
D
E
D
S
K
R
A
R
K
S
H
S
D
R
L
Honey Bee
Apis mellifera
XP_624050
1031
115155
P407
P
V
K
P
T
P
A
P
V
K
V
A
S
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795668
1146
126808
S477
D
D
A
D
V
S
E
S
N
V
E
E
D
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.9
87.8
N.A.
80.3
70.3
N.A.
N.A.
63.6
56.4
49
N.A.
23.3
25
N.A.
24.7
Protein Similarity:
100
99.6
98.1
92.1
N.A.
87.1
77.1
N.A.
N.A.
77.3
71.7
66.3
N.A.
42.7
44.4
N.A.
43.2
P-Site Identity:
100
100
100
0
N.A.
66.6
6.6
N.A.
N.A.
13.3
0
6.6
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
100
100
33.3
N.A.
73.3
6.6
N.A.
N.A.
40
20
46.6
N.A.
26.6
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
17
0
9
17
0
0
0
0
9
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
9
9
0
9
0
0
0
0
0
0
17
0
0
% D
% Glu:
34
17
0
9
17
0
34
0
0
9
17
50
9
25
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
9
0
25
25
0
0
0
0
17
9
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% I
% Lys:
0
34
17
0
17
9
25
25
42
25
0
0
0
34
17
% K
% Leu:
0
0
9
0
9
0
0
0
0
0
42
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
9
0
25
0
0
0
9
0
9
0
0
0
0
% N
% Pro:
9
9
0
9
0
9
0
9
0
0
0
25
9
0
0
% P
% Gln:
0
0
0
9
0
0
0
9
17
25
0
0
0
0
34
% Q
% Arg:
0
0
9
0
0
9
9
9
9
0
0
0
17
9
0
% R
% Ser:
0
0
0
17
9
50
9
50
0
9
0
9
9
9
17
% S
% Thr:
17
17
9
0
9
9
0
0
0
9
9
0
34
0
9
% T
% Val:
0
9
0
0
17
0
0
0
9
9
9
0
0
0
0
% V
% Trp:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _